DEPARTMENT OF LIFE SCIENCE

Dr. Sheeza Khan

Designation : Assistant Professor (Sr. Gr.)
Nature of Employment : Regular
Date of Joining : 09/07/2018
Qualification : NET and Ph.D.
Phone : 04422759215 Ext: 380
Email ID : sheezakhan.sls@crescent.eductation
Google Scholar Link : https://scholar.google.com/citations?user=5_Z2WHAAAAAJ&hl=en
Scopus Link : https://www.scopus.com/authid/detail.uri?authorId=55569674500
Orcid Id : 0000-0002-0654-4901
Educational Background
  • Ph. D. Protein Chemistry, CIRBS, Jamia Millia Islamia, New Delhi, India (2013)
  • M.Sc. Biosciences, Jamia Millia Islamia, New Delhi, India (2008)
  • B.Sc. Biotechnology, Jamia Millia Islamia, New Delhi, India (2006)
Teaching and research Experience
  • Assistant Professor (Senior Grade), BSACIST, Chennai, Tamil Nadu, India (2021-till date)
  • Assistant Professor, BSACIST, Chennai, Tamil Nadu, India (2018-2021)
  • Women Scientist (DST-WOS-A), ACBR, University of Delhi, Delhi, India (2017-2018)
  • Guest Faculty, Department of Biotechnology, Jamia Millia Islamia, New Delhi, India (2016-2017)
Honors and Awards
  • Selected as Women Scientist under Department of Science and Technology (DST) Women Scientist –A (WOS-A),2016.
  • Won first prize for oral presentation at “International Interdisciplinary Science Conference (I-ISC 2012) on Protein Folding and Diseases” organized by Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi- 110025, India.
  • Senior Research Fellowship (SRF-NET) awarded by the Council of Scientific and Industrial Research (CSIR), NewDelhifromJan,2012-Sept,2013.
  • Junior Research Fellowship (JRF-NET) awarded by the Council of Scientific and Industrial Research(CSIR), NewDelhif rom Jan.,2010-Dec,2011.
  • Qualified Nationality Eligibility Test (NET), June 2009 and secured a Rank- 178 in Subject- LifeSciences.
  • Awarded Merit Scholarship for 1st Rank in BSc.Biotechnology Second Year and also awarded Merit Scholarship from Jamia Hamdard for the same.
  • Awarded Merit Scholarship from Jamia Millia Islamia for 4th Rank in BSc. Biotechnology in First and Third Year.
Research areas
  • Protein Aggregation
  • Protein Folding and Stability
  • Protein folding intermediates
  • Protein folding in crowding environment
  • Protein purification
Research outcomes a. Research grants Ongoing Dr. Sheeza Khan, “Role of naturally occurring small molecules in transthyretin-induced familial amyloid cardiomyopathy”, DST WOS-A, 6,74,950 INR b. Publications Number of Research Publications
  • International journals: 08
  • National Journals: NIL
  • Conference presentations:15
  • Novel genomic sequences submitted to Genbank, NCBI, USA: NIL
  • Invited talks delivered: 02
  • Patents: Filed: Published: granted: NIL
List of publications
  • S. Khan, R. Kaushik, M.Sharma and A. Islam. Molecular basis of pathogenic parasitic infections: Insights from parasitekinome. Frontiers in Bioscience 1, 1488, 2020, (Scopus Indexed) (Impact Factor 2.17).www.imrpress.com/journal/FBL/25/8/10.2741/4865
  • R. Kaushik, S. KhanM. Sharma, S. Hemalatha, Z.Mueed and N. Poddar. Role of Cytochrome P450 in Prostrate Cancer and its Therapy.Current Enzyme Inhibition 16: 1, 2020, (Scopus Indexed) (Impact Factor 0.35).DOI: 10.2174/1573408016666200218122044
  • G. Sharma, S. KrishnaS. Khan, T. Dar, K.Khan and L. Singh. Protecting Thermodynamic Stability of Protein: The Basic Paradigm Against Stress and Unfolded Protein Response by Osmolytes. International Journal of Biological Macromolecules 177: 229-240, 2021, (Scopus Indexed) (Impact Factor 6.95. https://doi.org/10.1016/j.ijbiomac.2021.02.102
  • M.Basheeruddin, S. Khan, N.Ahmed and S. Jamal. Effect of pH on Diclofenac-Lysozyme interaction: Structural and Functional Aspect.Frontiers in Molecular Biosciences, section Molecular Diagnostics and Therapeutics. 9: 1-9, 2022, (Scopus Indexed) (Impact Factor 4.6). https://doi.org/10.3389/fmolb.2022.872905
  • N. Raina, S. Khan, S. Ranjani, S. Hemalatha, and Asimul Islam.Understanding the Nano Colloid-Protein Interaction in Crowded Milieu. Journal of Molecular Liquids. 363: 119794, 2022, (Scopus Indexed) (Impact Factor 6.63).https://doi.org/10.1016/j.molliq.2022.119794
  • S. Khan, T. Dar, and L. Singh. Clinical Implications of Osmolytes in Various Human DiseasesCellular Osmolytes, Springer, 2017.(ISBN978-981-10-3706-1)
  • S. Khan, and Ajaz A. Bhat. Non-Enzymatic post-translational Protein Modifications: Mechanisms and Associated Disease pathologies. Protein Modificomics: From Modifications to Clinical Perspectives, Elsevier, Springer, 2019.(ISBN 9780128119136)
  • S. Khan, Z. Mueed, R. Deval, P. Rai, and N. Poddar.  Role of osmolytes in amyloidosis. Synucleins- Biochemistry and Role in Diseases. Intech Open, 2019.(ISBN978-953-51-6474-6)
c. Research guidance Ph.D Ongoing: 01 Graduated: NIL
S. No. Name of the Scholar Title of Thesis Year of Registration Year of Completion Scholarship Details Outcomes
1 Ms. Ramya C Network Biology Approach to Decipher Type 2 Diabetes Mellitus and Its Associated Comorbidities 2022
M.Sc / M.Tech Completed : 17 Ongoing : 02
S. No. Name of the Scholar Title of Thesis Year of Registration Year of Completion Scholarship Details Outcomes
1 Ms. S. ShafreenAzhari To study the effect of β-alanine in opposing the destabilizing effect of urea on proteins 2018 2019
2 Ms. Shaily Singh Isolation of Endophytic fungi from the marine seaweed and screening for various biological activities 2019 2020 Conference Presentation: 01
3 Ms. Sakshi Srivastav Isolation and molecular characterization of multidrug resistance (MDR)Pseudomonas aeruginosa from clinical samples 2019 2020 Conference Presentation: 01
4 Ms. GousiaZamrood Comparing the effect of amino acid osmolyte on the stability of alpha-lactalbumin in the presence of Dextran 70 and Dextran 40 2020 2021 Conference Presentation: 01
5 Ms. Abitha Shree T.P. Understanding the effect of glucose-sorbitol mixtures on the functional activity of lysozyme 2021 2022
6 Mr. Aasim Zaid K Understanding the effect of oligosaccharides and their monosaccharide mixtures on the functional activity of lysozyme 2021 2022
7 Ms. Rajeshwari N Investigating the effect of glycine and alanine mixtures on the functional activity of lysozyme in the presence of Dextran 70 2021 2022
8 Mr. Saran M Development of Low Fidelity Virtualized Bio-Molecular Simulator for Lac Operon Gene Regulation 2021 2022
9 Mr. Marikar Mohammed Shafique Investigating the effect of urea-sorbitol mixtures on the functional activity of lysozyme in the presence of Ficoll 70 2021 2022
10 Ms. Vandana S Comparing thermal stability of alpha-lactalbumin in the presence of disaccharide osmolytes and their constitutive monosaccharide unit mixtures in the presence of Dextran 70 2022 2023 Conference Presentation: 02
11 Ms. R. Archana Comparing the effect of polyol osmolytes on the thermal stability of alpha-lactalbumin in the presence of different sizes of polyethylene glycol 2022 2023 Conference Presentation: 02
12 Ms. Harini B Investigating the effect of salt-methylamine mixtures on protein stability on crowded mileu 2022 2023 Conference Presentation: 01
13 Ms. R.R. Saranya Methylated glycine counters urea-induced protein destabilization 2022 2023 Conference Presentation: 01
14 Mr. Karthikeyan L Comparing the effect of amino acid osmolyte on the thermal stability of RNase-A in presence of Dextran 70 and Dextran 40 2022 2023 Conference Presentation: 01
15 Ms. Vijayalakshmi J Evaluation of breast cancer with Her2/NEU gene amplification using FISH 2022 2023 Conference Presentation: 01
16 Ms. Sindhu K Investigating the effect of taurine and urea mixtures on the stability of RNase-a in the crowded environment 2022 2023 Conference Presentation: 01
17 Ms. Samya P Role of methylamine osmolytes in counteracting ethanol stress in crowded environment 2022 2023 Conference Presentation: 01
B.Tech Completed : 09 Ongoing : NA
S. No. Name of the Scholar Title of Thesis Year of Registration Year of Completion Scholarship Details Outcomes
1 Ms.JanetRefona Effect of equimolar polyol mixtures on the stability of RNase-A 2019 2020 Conference Presentation: 01
2 Ms. Mancy Augustine Effect of equimolar amino acid osmolyte mixtures on the stability of RNase-A 2019 2020 Conference Presentation: 01
3 Ms. Dhanusha D Investigating the effect of amino acid osmolyte mixtures on the stability of alpha-lactalbumin in the presence of Dextran 70 2020 2021 Conference Presentation: 01
4 Mr. T. Mohammed Imaad Khan Investigating the effect of urea and sorbitol mixtures on the stability of alpha-lactalbumin in the presence and absence of Dextran 70 2020 2021 Conference Presentation: 01
5 Ms. Mydeen Fatima Investigating the effect of sugar and polyol mixtures on the stability of alpha-lactalbumin 2020 2021 Conference Presentation: 01
6 Ms. Niveditha Sridhar Investigating the effect of glycine and sucrose mixtures on the stability of alpha-lactalbumin 2020 2021 Conference Presentation: 01
7 Ms. Princy J Investigating the effect of Taurine and Myo-inositol mixtures on the stability of alpha-lactalbumin in the presence of Dextran 70 2020 2021 Conference Presentation: 01
8 Ms. Sri Vasunthara U Investigating the effect of taurine and β-alanine mixtures on the stability of alpha-lactalbumin 2020 2021 Conference Presentation: 01
9 Mr. Lokprakash Aravindan Anti-diabetic potential of ipomea batatas using zebra fish 2021 2022