SCHOOL OF LIFE SCIENCES
Life Science
Dr. Shazia Jamal
 |
| Designation | : | Associate Professsor |
| Nature of Employment | : | Regular |
| Date of Joining | : | 19/09/2013 |
| Qualification | : | M.Sc.,Ph.D |
| Phone | : | 9176902019 |
| Email ID | : | shazia.sls@crescent.education |
| Google Scholar link | : | https://scholar.google.com/citations?user=j16UMo0AAAAJ&hl=en |
| Scopus Link | : | https://www.scopus.com/authid/detail.uri?authorId=55771032000 |
| Orcid Id | : | ORCID: 0000-0003-4555-9513 |
Educational Background
- Ph.D-Jamia Millia Islamia, New Delhi, India (2010)
- M.Phil Name of the institution, Year of award of the degree-NA
- M.Sc-Aligarh Muslim University, Aligarh, India (2004)
- B.Sc-Aligarh Muslim University, Aligarh, India (2002)
Teaching and research Experience
- Associate Professor in BSA Crescent Institute of Science and Technology, Chennai, India (31.08.2022 to Till Date)
- Assistant Professor (Selection Grade) in BSA Crescent Institute of Science and Technology, Chennai, India (Jan 2020 to 30.08.2022)
- Assistant Professor (Senior Grade) in BSA Crescent Institute of Science and Technology, Chennai, India (Sept 2013 to Jan 2020)
- Postdoctoral Research Fellow at Karmanos Cancer Institute, Wayne State University, USA (2011-2013)
Honors and Awards
- Senior Research Fellowship (2008-2010) awarded by the UGC, India.
- Junior Research Fellowship (2005-2007) awarded by the UGC, India.
- Qualified NET-JRF (2005) awarded by UGC, India.
- Masters Fellowship (2002-2004) awarded by Department of Biotechnology, Govt of India.
Research areas
- Protein Biochemistry
- Protein aggregation
- Biophysics
- Protein Engineering
- Protein folding
- Targeted Cancer Therapy
- Cell cycle & Apoptosis
- Enzyme Kinetics
Research outcomes
a. Research grants
Completed
- Shazia Jamal, “To study the effect of Diclofenac and Osmolytes on protein stability in Renal Dysfunction” DST-SERB, 2014-2017, 1,36,000 INR
b. Publications
Number of Research Publications
- International journals: 26
- Conference presentations: 44
- Invited talks delivered: 02
List of publications
- Bommanaboina Anil Kumar, Neesar Ahmed, Shazia Jamal.* Biosynthesis and Characterization of Silver Nanoparticles (AgNPs) with Jacalin, lectin from Jackfruit seeds and its anti-proliferative effects on HeLa cancer cells. Letters in Applied NanoBioScience. 2023. (Scopus Indexed) (Impact Factor 1.9). Accepted (In Press). (Q3)
- Basheeruddin, Mohd, V. Lavanya, Neesar Ahmed, and Shazia Jamal. “Organic osmolyte betaine mitigates the deleterious effects of Diclofenac in vivo in wistar albino rats.” Brazilian Journal of Pharmaceutical Sciences 59, 2023. https://doi.org/10.1590/s2175-97902023e201178 (Scopus Indexed) (Impact Factor 0.6) (Q2)
- Mohd. Basheeruddin, Neesar Ahmed, Md Khurshid Alam Khan, and Shazia Jamal.* Betaine, an Organic Osmolyte Effectively Counteracts the Deleterious Effect of Diclofenac on Protein Structure and Stability. Biophysics J. 68, 356-364, 2023. e201178, 2023. https://doi.org/10.1590/s2175-97902023e201178 (Scopus Indexed) (Impact Factor 0.6) (Q2)
- AK Bommanaboina, S Jamal, N Ahmed.* Antitumor Activity of Taxol Engross Taxol-Caveolin-1 Interaction via Lipid Raft Structure—“Caveolae”. Applied Biochemistry and Biotechnology. 1-12, 2023. https://doi.org/10.1007/s12010-023-04355-7 (Scopus Indexed) (Impact Factor 3.09) (Q2)
- Mohd Basheeruddin, S Khan, S Jamal. Effect of pH on Diclofenac–Lysozyme Interaction: Structural and Functional Aspect. Frontiers in Molecular Biosciences, 9, 2022. https://doi.org/10.3389/fmolb.2022.872905 (Scopus Indexed) (Impact Factor 4.0) (Q1)
- Logesh, V. Lavanya, S. Jamal, N. Ahmed. Designing of a Chimeric Vaccine Using EIS (Rv2416c) Protein Against Mycobacterium tuberculosis H37Rv: an Immunoinformatics Approach. Applied Biochemistry and Biotechnology, 194 (1), 187–214, 2022. https://link.springer.com/article/10.1007/s12010-021-03760-0 (Scopus Indexed) (Impact Factor 3.1). (Q2)
- Lavanya, A.K. Bommanaboina, N. Ahmed, S. Jamal. Immunomodulatory Effects of Jacalin, a Dietary Plant Lectin on the Peripheral Blood Mononuclear Cells (PBMCs). Applied Biochemistry and Biotechnology, 194 (1), 587–599, 2022. https://link.springer.com/article/10.1007/s12010-021-03722-6 (Scopus Indexed) (Impact Factor 3.1). (Q2)
- J. Kashifa Fathima, V. Lavanya, S. Jamal, N. Ahmed. The Effectiveness of Various Chemotherapeutic Agents in Cancer Treatment. Current Pharmacology Reports, 1–17, 2022. https://link.springer.com/article/10.1007/s40495-022-00289-6 (Scopus Indexed) (Impact Factor 2.2). (Q3)
- M. Gayathri, V. Lavanya, S. Jamal, N. Ahmed. Targeting Soluble Factors Involved in Inflammatory Cancer Microenvironment. Current Pharmacology Reports, 1–9, 2022. https://link.springer.com/article/10.1007/s40495-022-00291-y (Scopus Indexed) (Impact Factor 2.2). (Q3)
- V. Lavanya, S. Jamal, N. Ahmed. Increased ERK phosphorylation and caveolin-1 expression on K562 human chronic myelogenous leukemia cells by jacalin, a dietary plant lectin. Glycoconjugate Journal, 38 (3), 361–368, 2021. https://pubmed.ncbi.nlm.nih.gov/33835346/ (Scopus Indexed) (Impact Factor 2.7). (Q3)
- A.A. Adil, A.K. Bommanaboina, A. Vaithy, S. Kumar, M. Waseem, S. Jamal, N. Ahmed. Differential expression of Helios, Neuropilin-1 and FoxP3 in head and neck squamous cell carcinoma (HNSCC) patients. 3 Biotech, 9 (5), 1–10, 2019. https://pubmed.ncbi.nlm.nih.gov/30997315/ (Scopus Indexed) (Impact Factor 2.9). (Q2)
- A.A.M. Adil, L. Vallinayagam, K. Chitra, S. Jamal, A.K. Pandurangan, N. Ahmed. Increased Expression of TGF-β and IFN-γ in Peripheral Blood Mononuclear Cells (PBMCs) Cultured in Conditioned Medium (CM) of K562 Cell Culture. Journal of Environmental Pathology, Toxicology and Oncology, 38 (2), 2019. https://pubmed.ncbi.nlm.nih.gov/31679280/ (Scopus Indexed) (Impact Factor 2.9). (Q3)
- Mohamed Adil, A.A., V. Anandraj, S. Kumar, M. Waseem, K. Chitra, B.A. Kumar. Role of mesenchymal cells and immunosuppressive cells within inflammatory tumor microenvironment. J Hematol Oncol Forecast, 1 (1), 1005, 2018. https://www.researchgate.net/publication/333079127_Role_of_Mesenchymal_Cells_and_Immunosuppressive_Cells_within_Inflammatory_Tumor_Microenvironment (Scopus Indexed) (Q1)
- V. Lavanya, B.A. Kumar, S. Jamal, M.K.A. Khan, N. Ahmed. Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin. The Protein Journal, 36 (1), 17–27, 2017. https://pubmed.ncbi.nlm.nih.gov/28133706/ (Scopus Indexed) (Impact Factor 2.3). (Q1)
- Lavanya V, Md. Khurshid Alam, Neesar Ahmed, Shazia Jamal. Sustained mitogenic effect on K562 human chronic myelogenous leukemia cells by dietary lectin, jacalin. Glycoconjugate Journal, 33(6), 877-886, 2016. https://pubmed.ncbi.nlm.nih.gov/27540731/ (Scopus Indexed) (Impact Factor 2.7). (Q3)
- Adil, V. Lavanya, S. Jamal, N. Ahmed. Cancer immunotherapy: Targeting immunosuppressive tumor microenvironment. Oncobiology and Targets, 1 (1), 16–16, 2014 https://www.researchgate.net/publication/285028462_Cancer_immunotherapy_Targeting_immunosuppressive_tumor_microenvironment (Scopus Indexed)
- V. Lavanya, A.M. Adil, N. Ahmed, S. Jamal. Lectins—the promising cancer therapeutics. Oncobiology and Targets, 1 (1), 12–12, 2014 https://go.gale.com/ps/i.do?id=GALE%7CA477320485&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=&p=AONE&sw=w&userGroupName=tel_oweb&isGeoAuthType=true&cookieConsent=true&analyticsOptout=false&aty=geo (Scopus Indexed)
- V. Lavanya, A.M. Adil, N. Ahmed, S. Jamal. Small molecule inhibitors as emerging cancer therapeutics. Integrative Cancer Science and Therapy, 1 (3), 39–46, 2014. https://www.oatext.com/small-molecule-inhibitors-as-emerging-cancer-therapeutics.php (Scopus Indexed) (Impact-Factor: 1.981) (Q3)
- Cheriyan, V.T., Wang, Y., Muthu, M., Jamal, S., Chen, D., Yang, H., Polin, L.A., Tarca, A.L., Pass, H.I., Dou, Q.P., Sharma, S., Wali, A., Rishi, A.K. Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis. PLoS One, 9 (4), Apr 1, 2014. https://doi.org/10.1371/journal.pone.0093711 (Scopus Indexed) (Impact-Factor 2.6). (Q1)
- Jamal, S., Cheriyan, V.T., Muthu, M., Munie, S., Levi, E., Ashour, A.E., Pass, H.I., Wali, A., Singh, M., Rishi, A.K. CARP-1 Functional Mimetics Are a Novel Class of Small Molecule Inhibitors of Malignant Pleural Mesothelioma Cells. PLoS One, 9 (3), Mar 5, 2014. https://doi.org/10.1371/journal.pone.0089146 (Scopus Indexed) (Impact-Factor: 2.6). (Q1)
- Ashour, A.E., Abdallah, A.R., Korashy, H.M., Attia, S.M., Alzahrani, A.Z., Saquib, Q., Bakheet, S.A., Abdel-Hamied, H.E., Jamal, S., Rishi, A.K. Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis. Molecular and Cellular Biochemistry, 389 (1–2), 85–98, 2014. https://pubmed.ncbi.nlm.nih.gov/24399465/ (Scopus Indexed) (Impact-Factor: 3.5). (Q2)
c. Research guidance:
Ph.D
Graduated : 02, Ongoing: 02
List of Scholars completed
| S.No | Name of the scholar | Title of the thesis | Year of registration | Year of Completion | Scholarship details | Outcomes |
| 1 | Lavanya V | Biophysical Analysis and Investigation of the Immunomodulatory and Mitogenic Facets of Jacalin | 2013 | 2018 | BSACIST Scholarship | Publications: 06 Conference presentations: 09 |
| 2 | Mohd Basheeruddin | Protective Effect of Osmolytes on Diclofenac Induced Changes in Protein Stability: Structural, Functional and Thermodynamic Aspects | 2014 | 2023 | DST-JRF | Publications: 03 Conference presentations: 08 |
List of Scholars ongoing
| S.No | Name of the scholar | Title of the thesis | Year of registration | Scholarship details | Outcomes |
| 1 | Parveen A | Isolation and characterization of fibrinolytic enzyme from marine bacteria for therapeutic application in cardiovascular diseases | 2024 | DSTWISE-PhD project | Conference presentations: 05 |
| 2 | Parvathavardhini P | Investigating the Protective Roles of Polyphenols and Osmolytes in Preventing Protein Aggregation: From Molecular Pathways to ClinicalApplications | 2023 | BSACIST Scholarship | Conference presentations: 02 |
M.Sc/M.Tech
Completed projects: 25, Ongoing projects : 3 (Number only)
M.Sc/M.Tech
Completed projects: 31
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
| 1. | Reeshma Fathima A | Effects Of Dietary Polyphenols from Cocoa Powder In Modulating Protein Aggregation | 2025 | Conference presentations: 02 |
| 2. | Dhiya Mariyam K | Investigating the Effects of Polyphenols Present in Blueberries in Protein Aggregation | 2025 | Conference presentations: 02 |
| 3. | MD Sibgatullah Ansari | pH Dependent Effects of Polyols in Preventing the aggregation of protein | 2025 | Conference presentations: 01 |
| 4. | Sangeetha R | Nanoparticle coated food preservation sheets | 2024 | Conference presentations: 01 |
| 5. | Suganya K | Purification of keratin from pigeon feathers and formulation of hair products. | 2024 | Conference presentations: 01 |
| 6. | Karthik M | Comparative Study and Preparation of Snacks Bar in Black Rice with Sunflower Seed, Soybean, And Lotus Seed | 2024 | Conference presentations: 01 |
| 7. | Satheesh S | Estimation of Bacterial Inhibition Activity of Curcumin Copper Nanoparticles | 2023 | Conference presentations: 04 |
| 8. | Kirthika M | Study On the Effect of Noval Oral Anti-Coagulants (Noacs) Drug on Pepsin Stability | 2023 | Conference presentations: 01 |
| 9. | Aafrin Akthar | Comparative Study of Antimicrobial and Anticancer Activity of Clove and Lemon | 2023 | Conference presentations: 01 |
| 10. | Divya | Estimation of Bacterial Inhibition Activity of Curcumin Silver Nanoparticles | 2023 | Conference presentations: 01 |
| 11. | Nikkath Mahira | A comparative study of antimicrobial and anticancer activity of flavonoids | 2023 | Conference presentations: 01 |
| 12. | Parvathavardhini | To study the effect of antidepressant drug on histone protein stability | 2023 | Conference presentations: 01 |
| 13. | Parveen Shanofer | Macerated Herbal Oil-Infusion of Oil with Medicinal Herbs and Their Subsequent Analysis | 2023 | Conference presentations: 01 |
| 14. | Mohamed Asif Salman | Biosynthesis of Silver Nanoparticle using Psidium Guajava aqueous solution and incorporated into Chitosan for food preservation | 2023 | Conference presentations: 01 |
| 15. | Fayith Rahman. U | Extraction And Application of Zingiber officinale, Citrus limon and Syzygium aromaticum, to serve as medicinal candy | 2021 | Conference presentations: 01 |
| 16. | Karthik D | Inhibiting marine bacterial enzymes to overcome the degradation of seaweed hydrocolloids | 2021 | Conference presentations: 01 |
| 17. | Mohana Sundaram | Anti-microbial activities of chitosan and Zinc Oxide nanoparticles loaded gallic-acid films on meat packaging material | 2021 | Conference presentations: 01 |
| 18. | Rahul D | Green synthesis of silver and Zinc oxide nanoparticles and nanoparticle coating on glass material | 2021 | Conference presentations: 01 |
| 19. | Divyesh Kumar .K | Green Synthesis of Iron Oxide Nano Particles using Carciaca papaya leaf extract | 2021 | Conference presentations: 01 |
| 20. | Karishma Sultana H | Formulation Of Anti-Bacterial Gel with Plant Extracts of Common Indian Herbs | 2021 | Conference presentations: 01 |
| 21. | Rajeshwari M | Green Synthesis of Zinc Oxide Nanoparticles from Acalypha Indica | 2021 | Conference presentations: 03 |
| 22. | Subiksha.P | Phytochemical Analysis and Invitro Anti-Inflammatory Activity of Different Extracts of Costus igneus Plant | 2021 | Conference presentations: 02 |
| 23. | Reshma M | Isolation and Molecular Identification of Alkaline Protease Producing Bacteria from Soil Sample | 2020 | Conference presentations: 02 |
| 24. | Arockia Alex | Assessment Of Antioxidant Activity of Capsule Polysaccharide from Colwellia psychrerythraea | 2020 | Conference presentations: 02 |
| 25. | T. Sumiya Begum | Microbes From Dust in Air Conditioner Filters: Isolation and Identification | 2020 | Conference presentations: 01 |
| 26. | Nithiya S | Antibacterial effect and Mode of action of Chlorogenic acid on Salmonella and Bacillus species | 2019 | Conference presentations: 01 |
| 27. | S. Harisutha | Isolation of Silver nanoparticle by using Artocarpus heterophyllus | 2019 | Conference presentations: 01 |
| 28. | Thasin Banu. A | Antimicrobial activity of some commercial fruits against UTI (urinary tract infection) | 2019 | Conference presentations: 02 |
| 29. | Abdullah Mohammed Ayedh Aladhreai | Studies of antimicrobial activity of methanolic extract of the leaves of Costus igneus | 2018 | Conference presentations: 04 |
| 30. | Hafeez Ahmad | Bio thermodynamic studies of Diclofenac interaction with Lysozyme at different pH | 2017 | Conference presentations: 03 |
| 31. | Farhana Fathima | Purification and Functional Characterization of Lectin from Edible Mushroom | 2016 | Conference presentations: 02 |
B.Tech
Completed projects: 37
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
| 1. | Mohammed Rifath F | Isolation of secondary metabolites from Padina boergesenii and its anti-cancer properties | 2025 | Conference presentations: 02 |
| 2. | Mohamed Naufal | Isolation of Secondary Metabolites from Hormophysa Cuneiformis and its anti-cancer properties | 2025 | Conference presentations: 02 |
| 3. | Sudharson S | Isolation of secondary metabolites from Phaseolus lunatus and identifying its anti-cancer properties | 2025 | Conference presentations: 02 |
| 4. | Abdul Kasam | GB Virus C/Hepatitis G Virus Envelope Glycoprotein E2: Computational Molecular Features and Immunoinformatics Study | 2024 | – |
| 5. | D. Pradhibraj | Identification of Novel Druggable Target in Burkholderia mallei using Substractive Proteomics and Drug Repurposing Approaches | 2024 | – |
| 6. | Hafsa Gulnaz | Extraction And Phytochemical Analysis of Proteins from Carica Papaya and evaluation Of Their Biological Activities | 2024 | Conference presentations: 01 |
| 7. | Pavithra J | Extraction And Phytochemical Analysis of Proteins from Pineapple Peel and Evaluation of their biological activities | 2024 | Conference presentations: 01 |
| 8. | Jeffery Jackson C | Effect Of Different Carbohydrates on the activity and stability of jacalin | 2024 | Conference presentations: 01 |
| 9. | Aquib R | Synthesis of Gold Nanoparticles and Detection of Lactic acid AuNP | 2023 | Conference presentations: 01 |
| 10. | Mridhula J | Analysis of Anticancer Potential of Clonidine Hydrochloride and 5-Fluorouracil in Colon Cancer | 2023 | Conference presentations: 01 |
| 11. | Theepika | Green synthesis of silver nano particles of leaf extract of Psidium Guajava and evaluation of their antibacterial activity along with docking analysis | 2022 | Conference presentations: 03 |
| 12. | Adhil | Interaction between protein and Non steroidal anti inflammatory drug- in silico and computational approach | 2022 | – |
| 13. | Bouvanesh.J | In-silico construction of Multi-Peptide Vaccine by using Rv3846 protein for simulating the Immune Response against Mycobacterium tuberculosis H37Rv; An immunoinformatic Approach. | 2021 | Conference presentations: 02 |
| 14. | D.Charumathi | Insilico Designing of Epitope Based Vaccine using FlagellinH1A Protein against Salmonella typhimurium | 2021 | Conference presentations: 02 |
| 15. | Dinagar R | Estimating Suitability of Glutathione S-Transferase for Pesticide Detection in Biosensor Applications Using Homology Modeling and Molecular Docking | 2021 | Conference presentations: 03 |
| 16. | Mohamutha Farshana.T | Formulation Of Oxygen Absorber for Food Preservation | 2021 | Conference presentations: 02 |
| 17. | P Neeraja | Isolation And Characterization Of R-Phycoerythrin, A Commercial and Natural Pigment from Red Sea Weeds (Kappaphycus alvarezii and Hypnea spicefera) | 2021 | Conference presentations: 03 |
| 18. | S.B.Parveen Shanofer | Synbioticmoisturizer- Role of Probiotics and Prebiotic in Skin Health | 2021 | Conference presentations: 03 |
| 19. | Janani.J | Extraction Of Keratin Protein from Pigeon Feathers and Estimation of Keratin Using Uv-Vis Spectrophotometer | 2021 | Conference presentations: 02 |
| 20. | Mohammed Ahmed | Synthesis Of Biofertilizer by Composting Method | 2021 | Conference presentations: 02 |
| 21. | Mohammed Atif | Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) And Protein Interaction | 2021 | Conference presentations: 02 |
| 22. | Mohamed Syed Shaik Ismail G | Optimization Of Cordycepys militaris in alternative medium and control medium | 2020 | Conference presentations: 01 |
| 23. | Rameeza Banu S | The phyto chemical analysis and the effect of soxhlet and. ultrasonic-assisted extraction on antioxidant content of Vigna radiata | 2020 | Conference presentations: 01 |
| 24. | Samrin Abdul Sathar | Green synthesis and characterization of zinc oxide nanoparticles using Calendula officinalis | 2020 | Publications: 01 Conference presentations: 02 |
| 25. | Selvaraj Mukesh | Formulation Of Energy Bar Using Three Varieties and sensory evaluation and to estimate shelf life | 2020 | Conference presentations: 01 |
| 26. | Haseena Begum P | Biodegradable Plastic Production from Fruit Waste Material | 2020 | – |
| 27. | Sobia Nida.E | Protein purification from seaweeds | 2019 | Conference presentations: 02 |
| 28. | Avanthika. K | Efficacy of nanoparticles in zebra fish | 2019 | Conference presentations: 01 |
| 29. | Priya.V | Hydrogel sheets efficacy in protecting infection | 2019 | Conference presentations: 01 |
| 30. | Sangeetha. C | Bromelain protein purification and characterization | 2019 | Conference presentations: 01 |
| 31. | Vinitha. B | Biophysical aspects of diclofenac with model proteins | 2019 | Conference presentations: 01 |
| 32. | Mohamed Ashick. S. | Hydrogel sheets of chitosan, honey with polymers as burn wound dressings | 2018 | Conference presentations: 03 |
| 33. | Sangeetha. P. | Biosynthesis of silver and zinc nanoparticles using Piper longum and its application in antibacterial activity | 2018 | Conference presentations: 03 |
| 34. | Sangeetha. R | Purification of jacalin from jackfruit seed (Artocarpus integrifolia) and its effect on immune response | 2018 | Conference presentations: 03 |
| 35. | Umamaheswari. V | Biosynthesis, characterization of iron oxide nanoparticles and evaluation of its cytotoxicity in cancer cell lines | 2018 | Conference presentations: 03 |
| 36. | Vinodhini.S | Probing the interaction of folic acid antagonist pyrimethanamine with model protein BSA: a biophysical investigation | 2018 | Conference presentations: 03 |
| 37. | Aparna Mohan | In vitro wound healing property of Collagen isolated from Rhizoprionodon acutus (Milk Shark) | 2018 | Conference presentations: 03 |
