DEPARTMENT OF LIFE SCIENCE
Life Science
Dr. Shazia Jamal
 |
| Designation | : | Associate Professsor |
| Nature of Employment | : | Regular |
| Date of Joining | : | 19/09/2013 |
| Qualification | : | M.Sc.,Ph.D |
| Email ID | : | shazia.sls@crescent.education |
| Google Scholar link | : | https://scholar.google.com/citations?user=j16UMo0AAAAJ&hl=en |
| Scopus Link | : | https://www.scopus.com/authid/detail.uri?authorId=55771032000 |
| Orcid Id | : | ORCID: 0000-0003-4555-9513 |
Educational Background
- Ph.D-Jamia Millia Islamia, New Delhi, INDIA (2010)
- M.Sc-Aligarh Muslim University, Aligarh, INDIA (2004)
- B.Sc-Aligarh Muslim University, Aligarh, INDIA (2002)
Teaching and research Experience
- Associate Professor in BSA Crescent Institute of Science and Technology, Chennai, India (31.08.2022 to current).
- Assistant Professor (Selection Grade) in BSA Crescent Institute of Science and Technology, Chennai, India (Jan 2020 to 30.08.2022).
- Assistant Professor (Senior Grade) in BSA Crescent Institute of Science and Technology, Chennai, India (Sept 2013 to Jan 2020).
- Postdoctoral Research Fellow at Karmanos Cancer Institute, Wayne State University, USA (2011-2013).
Honors and Awards
- Qualified NET-JRF (2005) awarded by UGC, India.
- Senior Research Fellowship (2008-2010) awarded by the UGC, India.
- Junior Research Fellowship (2005-2007) awarded by the UGC, India.
- Masters Fellowship (2002-2004) awarded by Department of Biotechnology, Govt of India.
Research areas
- Protein Biochemistry
- Biophysics
- Protein chemistry
- Protein folding
- Targeted Cancer Therapy
- Cell cycle & Apoptosis
- Targeted Cancer Therapy
- Cell cycle & Apoptosis
- Enzyme Kinetics
- Protein aggregation.
Research outcomes
a. Research grants
Completed
Dr. Shazia Jamal, “To study the effect of Diclofenac and Osmolytes on protein stability in Renal Dysfunction” DST-SERB, 1,36,000 INR
b. Publications
Number of Research Publications
- International journals: 22
- National journals: nil
- Conference presentations: 44
- Novel genomic sequences submitted to Genbank, NCBI, USA: nil
- Invited talks delivered: 02
- Patents: filed: Published: granted: nil
List of publications
- Mohd Basheeruddin, S Khan, S Jamal. Effect of pH on Diclofenac–Lysozyme Interaction: Structural and Functional Aspect. Frontiers in Molecular Biosciences 9 (2022). https://doi:10.3389/fmolb.2022.872905
- R Logesh, V Lavanya, S Jamal, N Ahmed. Designing of a Chimeric Vaccine Using EIS (Rv2416c) Protein Against Mycobacterium tuberculosis H37Rv: an Immunoinformatics Approach. Applied Biochemistry and Biotechnology 194 (1), 187-214 (2022). https://doi.org/10.1007/s12010-021-03760-0.
- V Lavanya, AK Bommanabonia, N Ahmed, S Jamal. Immunomodulatory Effects of Jacalin, a Dietary Plant Lectin on the Peripheral Blood Mononuclear Cells (PBMCs). Applied Biochemistry and Biotechnology 194 (1), 587-599 (2022). https://doi.org/10.1007/s12010-021-03722-6
- J Kashifa Fathima, V Lavanya, S Jamal, N Ahmed. The Effectiveness of Various Chemotherapeutic Agents in Cancer Treatment. Current Pharmacology Reports, 1-17 (2022). https://doi.org/10.1007/s40495-022-00289-6
- M Gayathri, V Lavanya, S Jamal, N Ahmed. Targeting Soluble Factors Involved in Inflammatory Cancer Microenvironment. Current Pharmacology Reports, 1-9 (2022). https://doi.org/10.1007/s40495-022-00291-y
- V Lavayna, S Jamal, N Ahmed. Increased ERK phosphorylation and caveolin-1 expression on K562 human chronic myelogenous leukemia cells by jacalin, a dietary plant lectin.. Glycoconjugate Journal 38 (3), 361-368 (2021). https://doi.org/10.1007/s10719-021-09998-4
- AA Adil, AK Bommanabonia, A Vaithy, S Kumar, M Waseem, S Jamal, N Ahmed. Differential expression of Helios, Neuropilin-1 and FoxP3 in head and neck squamous cell carcinoma (HNSCC) patients. 3 Biotech 9 (5), 1-10 (2019). https://doi.org/10.1007/s13205-019-1707-7
- AAM Adil, L Vallinayagam, K Chitra, S Jamal, AK Pandurangan, N Ahmed. Increased Expression of TGF-β and IFN-γ in Peripheral Blood Mononuclear Cells (PBMCs) Cultured in Conditioned Medium (CM) of K562 Cell CultureJournal of Environmental Pathology, Toxicology and Oncology 38 (2) (2019). https://doi.org/10.1615/JEnvironPatholToxicolOncol.2019029460
- V Lavanya, BA Kumar, S Jamal, MKA Khan, N Ahmed. Sub-Micellar Concentration of Sodium Dodecyl Sulphate Prevents Thermal Denaturation Induced Aggregation of Plant Lectin, Jacalin.The protein journal36 (1), 17-27 (2017). https://Doi.org/10.1007/s10930-017-9694-1
- Lavanya V, Md. Khurshid Alam, Neesar Ahmed, Shazia Jamal Sustained mitogenic effect on K562 human chronic myelogenous leukemia cells by dietary lectin, jacalin.Glycoconj. J (2016). https://DOI 10.1007/s10719-016-9725-8. https://Doi.org/10.1007/s10719-016-9725-8
- Adil, V Lavanya, S Jamal, N Ahmed. Cancer immunotherapy: Targeting immunosuppressive tumor microenvironment. Oncobiology and Targets 1 (1), 16-16 (2014). https://doi.org/10.1371/journal.pone.0093711
- V Lavanya, AM Adil, N Ahmed, S Jamal. Lectins-the promising cancer therapeutics. Oncobiology and Targets 1 (1), 12-12 (2014). (NA)
- V Lavanya, AM Adil, N Ahmed, S Jamal. Small molecule inhibitors as emerging cancer therapeutics.Integr Cancer Sci Ther 1 (3), 39-46 (2014). (NA)
- Cheriyan VT, Wang Y, Muthu M, Jamal S, Chen D, Yang H, Polin LA, Tarca AL, Pass HI, Dou QP, Sharma S, Wali A, Rishi AK. Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.PLoS One. Apr 1;9(4) (2014). https://doi.org/10.1371%2Fjournal.pone.0093711
- Jamal S, Cheriyan VT, Muthu M, Munie S, Levi E, Ashour AE, Pass HI, Wali A, Singh M, Rishi AK. CARP-1 Functional Mimetics Are a Novel Class of Small Molecule Inhibitors of Malignant Pleural Mesothelioma Cells. PLoS One. Mar 5;9(3) (2014). https://doi.org/10.1371%2Fjournal.pone.0089146
- Ashour, AE., Abdallah, AR., Korashy, HM., Attia, SM., Alzahrani AZ, Saquib Q, Bakheet SA, Abdel-Hamied HE, Jamal S and Rishi AK. Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis. Molecular and Cellular Biochemistry. Apr; 389(1-2), 85-98 (2014). https://doi.org/10.1007/s11010-013-1930-1
c. Research guidance:
Ph.D
Graduated : 01
Ongoing: 01
List of Scholars completed
| S.No | Name of the scholar | Title of the theis | Year of registration | Year of Completion | Scholarship details | Outcomes |
|---|---|---|---|---|---|---|
| 1 | Lavanya V | Biophysical Analysis and Investigation of the Immunomodulatory and Mitogenic Facets of Jacalin | 2013 | 2018 | BSAU Scholarship | Publications: 06 Conference presentations: 09 |
List of Scholars ongoing
| S.No | Name of the scholar | Title of the theis | Year of registration | year of Completion | Scholarship details | Outcomes |
|---|---|---|---|---|---|---|
| 1 | Mohd Basheeruddin | Protective Effect of Osmolytes on Diclofenac Induced Changes in Protein Stability: Structural, Functional and Thermodynamic Aspects | 2014 | – | DST-JRF | Publications: 03, Conference presentations: 08 |
M.Sc/M.Tech
Completed projects: 25, Ongoing projects : 3 (Number only)
M.Sc/M.Tech
Completed projects:
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
|---|---|---|---|---|
| 1. | Farhana fathima | Purification and Functional Characterization of Lectin from Edible Mushroom | 2016 | Conference presentations: 02 |
| 2. | Hafeez Ahmad | Bio thermodynamic studies of Diclofenac interaction with Lysozyme at different pH | 2017 | Conference presentations: 03 |
| 3. | Abdullah Mohammed Ayedh Aladhreai | Studies of antimicrobial activity of methanolic extract of the leaves of costus igneus | 2018 | Publications: 01 Conference presentations: 04 |
| 4. | Nithiya S | Antibacterial effect and Mode of action of Chlorogenic acid on Salmonella and Bacillus species | 2019 | communicated Conference presentations: 01 |
| 5. | S. Harisutha | Isolation of Silver nanoparticle by using artocarpus heterophyllus | 2019 | Conference presentations: 01 |
| 6. | Thasin Banu. A | Antimicrobial activity of some commercial fruits against UTI (urinary tract infection) | 2019 | Conference presentations: 02 |
| 7. | Reshma M | Isolation and Molecular Identification of Alkaline Protease Producing Bacteria from Soil Sample | 2020 | Conference presentations: 02 |
| 8. | AROCKIA ALEX | Assessment of Antioxidant Activity of Capsule Polysaccharide from Colwellia Psychrerythraea | 2020 | Conference presentations: 02 |
| 9. | T. SUMIYA BEGUM | MICROBES FROM DUST IN AIR CONDITIONER FILTERS: ISOLATION AND IDENTIFICATION | 2020 | Conference presentations: 01 |
| 10. | Fayith Rahman. U | EXTRACTION AND APPLICATION OF Zingiber officinale,Citrus limon AND Syzygium aromaticum,TO SERVE AS MEDICINAL CANDY | 2021 | Conference presentations: 01 |
| 11. | Karthik D | Inhibiting marine bacterial enzymes to overcome the degradation of seaweed hydrocolloids | 2021 | Conference presentations: 01 |
| 12. | Mohana Sundaram | Anti-microbial activities of chitosan and Zinc Oxide nanoparticles loaded gallic-acid films on meat packaging material | 2021 | Conference presentations: 01 |
| 13. | Rahul D | Green synthesis of silver and Zinc oxide nanoparticles and nanoparticle coating on glass material | 2021 | Conference presentations: 01 |
| 14. | Divyesh Kumar .K | GREEN SYNTHESIS OF IRON OXIDE NANO PARTICLES USING CARCIACA PAPAYA LEAF EXTRACT | 2021 | Conference presentations: 01 |
| 15. | Karishma Sultana H | FORMULATION OF ANTI-BACTERIAL GEL WITH PLANT EXTRACTS OF COMMON INDIAN HERBS | 2021 | Conference presentations: 01 |
| 16. | Rajeshwari M | GREEN SYNTHESIS OF ZINC OXIDE NANOPARTICLES FROM ACALYPHA INDICA | 2021 | Conference presentations: 03 |
| 17. | Subiksha.P | PHYTOCHEMICAL ANALYSIS AND INVITRO ANTI-INFLAMMATORY ACTIVITY OF DIFFERENT EXTRACTS OF COSTUS IGNEUS PLANT | 2021 | Conference presentations: 02 |
| 18. | SATHEESH S | Estimation of Bacterial Inhibition Activity of Curcumin Copper Nanoparticles | 2023 | Conference presentations: 04 |
| 19. | KIRTHIKA M | Study On The Effect Of Noval Oral Anti-Coagulants (Noacs) Drug On Pepsin Stability | 2023 | Conference presentations: 01 |
| 20. | AAFRIN AKTHAR | Comparitive Study Of Antiicrobial And Anticancer Activity Of Clove And Lemon | 2023 | Conference presentations: 01 |
| 21. | DIVYA | Estimation of Bacterial Inhibition Activity of Curcumin Silver Nanoparticles | 2023 | Conference presentations: nil |
| 22. | NIKKATH MAHIRA | A comparative study of antimicrobial and anticancer activity of flavoids | 2023 | Conference presentations: 01 |
| 23. | PARVATHAVARDHINI | To study the effect of antidepressant drug on histone proten satbility | 2023 | Conference presentations: 01 |
| 24. | PARVEEN SHANOFER | MACERATED HERBAL OIL-INFUSION OF OIL WITH MEDICINAL HERBS AND THEIR SUBSEQUENT ANALYSIS | Conference presentations: 01 | |
| 25. | MOHAMED ASIF SALMAN | Biosynthesis of Silver Nanoparticle using Psidium Guajava aqueous solution and incorporated into Chitosan for food preservation | 2023 | Conference presentations: 01 |
Ongoing projects
| S.No | Name of the student | Title of the project |
|---|---|---|
| 1. | Sangeetha R | Nanoparticle coated food preservation sheets |
| 2. | G. Srimathi | Formulation of wound dressings sheet using chitosan hydrogel |
| 3. | Suganya K | Purification of keratin from pigeon feathers and formulation of hair products. |
B.Tech
Completed projects: 29 ongoing projects : 05
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
|---|---|---|---|---|
| 1. | Mohamed Ashick. S. | hydrogel sheets of chitosan, honey with polymers as burn wound dressings | 2018 | Conference presentations: 03 |
| 2. | Sangeetha. P. | biosynthesis of silver and zinc nanoparticles using piper longum and its application in acntibacterial activity | 2018 | Conference presentations: 03 |
| 3. | Sangeetha. R | purification of jacalin from jackfruit seed (Artocarpus integrifolia) and its effect on immune response | 2018 | Conference presentations: 03 |
| 4. | Umamaheswari. V | biosynthesis, characterization of iron oxide nanoparticles and evaluation of its cytotoxicity in cancer cell lines | 2018 | Conference presentations: 03 |
| 5. | Vinodhini.S | probing the interaction of folic acid antagonist pyrimethanamine with model protein BSA: a biophysical investigation | 2018 | Conference presentations: 03 |
| 6. | Aparna Mohan | In vitro wound healing property of Collagen isolated from Rhizoprionodon acutus (Milk Shark) | 2018 | Conference presentations: 03 |
| 7. | Sobia Nida.E | Protein purification from seaweeds | 2019 | Conference presentations: 02 |
| 8. | Avanthika. K | Efficacy of nanoparticles in zebra fish | 2019 | Conference presentations: 01 |
| 9. | Priya.V | Hydrogel sheets efficacy in protecting infection | 2019 | Conference presentations: 01 |
| 10. | Sangeetha. C | Bromelain protein purification and characterization | 2019 | Conference presentations: 01 |
| 11. | Vinitha. B | Biophysical aspects of diclofenac with model proteins | 2019 | Conference presentations: 01 |
| 12. | Mohamed Syed Shaik Ismail G | Optimization Of Cordycepys Militaris In Alternative Medium And Control Medium | 2020 | Conference presentations: 01 |
| 13. | Rameeza Banu S | The phyto chemical analysis and the effect of soxhlet and .ultrasonic-assisted extraction on antioxidant content of vigna radiata | 2020 | Conference presentations: 01 |
| 14. | Samrin Abdul Sathar | Green synthesis and characterization of zinc oxide nanoparticles using Calendula officinalis | 2020 | Publications: communicated-01 Conference presentations: 02 |
| 15. | Selvaraj Mukesh | Formulation Of Energy Bar Using Three Varieties And Sensory Evaluation And To Estimate Shelf Life | 2020 | Publications: nil communicated Conference presentations: 01 |
| 16. | Haseena Begum P | Biodegradable Plastic Production From Fruit Waste Material | 2020 | – |
| 17. | Bouvanesh.J | In-silico construction of Multi-Peptide Vaccine by using Rv3846 protein for simulating the Immune Response against Mycobacterium tuberculosis H37Rv; An immunoinformatic Approach. | 2021 | Conference presentations: 02 |
| 18. | D.Charumathi | Insilico Designing of Epitope Based Vaccine using FlagellinH1A Protein against Salmonella typhimurium | 2021 | Conference presentations: 02 |
| 19. | Dinagar R | Estimating Suitability Of Glutathione S-Transferase For Pesticide Detection In Biosensor Applications Using Homology Modeling And Molecular Docking | 2021 | Conference presentations: 03 |
| 20. | Mohamutha Farshana.T | Formulation Of Oxygen Absorber For Food Preservation | 2021 | Conference presentations: 02 |
| 21. | P Neeraja | Isolation And Characterization Of R-Phycoerythrin,A Commercial And Natural Pigment From Red Sea Weeds (Kappaphycus Alvarezii And Hypnea Spicefera) | 2021 | Conference presentations: 03 |
| 22. | S.B.Parveen Shanofer | Synbioticmoisturizer- Role Of Probiotics And Prebiotic In Skin Health | 2021 | Conference presentations: 03 planning to file patent |
| 23. | Janani.J | Extraction Of Keratin Protein From Pigeon Feathers And Estimation Of Keratin Using Uv-Vis Spectrophotometer | 2021 | Conference presentations: 02 |
| 24. | Mohammed Ahmed | Synthesis Of Biofertilizer By Composting Method | 2021 | Conference presentations: 02 |
| 25. | Mohammed Atif | Non-Steroidal Anti-Inflammatory Drugs (Nsaids) And Protein Interaction | 2021 | Conference presentations: 02 |
| 26. | Theepika | Green synthesis of silver nano particles of leaf extract of Psidium Guajava and evaluation of their antibacterial activity along with docking analysis | 2022 | Conference presentations: 03 |
| 27. | Adhil | Interaction between protein and Non steroidal anti inflammatory drug- insilico and computational approach | 2022 | Conference presentations: nil |
| 28. | Aquib R | Synthesis of Gold Nanoparticles and Detection of Lactic acid AuNP | 2023 | Conference presentations: 01 |
| 29. | Mridhula J | Analysis of Anticancer Potential of Clonidine Hydrochloride and 5-Fluorouracil in Colon Cancer | 2023 | Conference presentations: 01 |
Ongoing projects :05
| S.No | Name of the student | Title of the project (tentative) |
|---|---|---|
| 1. | Abdul Kasam Khan | Protein aggregation and role of osmolytes to protect aggregation |
| 2. | Jeffery Jackson C | Synthesis of thermostable protein and its application |
| 3. | Pradhibraj D | Synthesis of nanoparticles from pure protein and its application |
| 4. | Pavithra J | Enzyme kinetics and application in food industry |
| 5. | Hafsa Gulnaz A | Misfolded protein and application of osmolytes for refolding |
