SCHOOL OF LIFE SCIENCES
Life Science
Dr. S.M.Fazeela Mahaboob Begum
 |
| Designation | : | Assistant Professor |
| Nature of Employment | : | Regular |
| Date of Joining | : | 05/05/2022 |
| Qualification | : | M.Sc., M.Phil., Ph.D |
| Phone | : | 8056197490 |
| Email ID | : | fazeelabegum@crescent.education |
| Google Scholar link | : | https://scholar.google.com/citations?hl=en&user=U7blc4cAAAAJ |
| Scopus Link | : | https://www.scopus.com/authid/detail.uri?authorId=57214545607 |
| Orcid Id | : | 0000-0003-4053-355X |
Educational Background
- Ph.D – B S Abdur Rahman Institute of Science and Technology, Chennai, 2018
- M.Phil – Manonmanium Sundaranar University, Tirunelvelli, 2003
- M.Sc – Madurai Kamaraj University, Madurai. 2000
- B.Sc – Madurai Kamaraj University, Madurai, 1998
Teaching and research Experience
- B S Abdur Rahman Crescent Institute of Science and Technology, Chennai, Assistant Professor, May 2022 to Present
- New Prince Shri Bhavani Arts and Science College, Chennai, Assistant Professor (Biochemistry) June 2019 to April 2022
- Dhanapalan College of Arts and Science, Chennai, Assistant Professor (Biochemistry), June 2013 to March 2014
- B S Abdur Rahman Crescent Institute of Science & Technology, Chennai, Senior Research Fellow, 2017 – 2018
- B S Abdur Rahman Crescent Institute of Science & Technology, Chennai, Junior Research Fellow, Chennai, 2014 – 2017
- Bharathidasan University, Trichy, Junior Research Fellow, 2007 -2009
- Nadar Saraswathi College of Arts and Science, Theni, Lecturer, August 2000 to June 2003
Honors and Awards
- Best Oral presentation award at the National conference on biotechnological advances in biomedical, Environmental and agricultural technology organized by Dept. of Biotechnology, Hindustan College of Arts and Sciences- Chennai, February 12, 2025
- Best Poster Award at the International Symposium in Fostering Skill Development in the Biotech Industry: A Path to Success, sponsored by Department of Biotechnology (DBT-CTEP), Government of India organized by the Department of Biotechnology, School of Life Science, Vels Institute of Science, Technology and Advanced Studies, Chennai, in association with INTI International University, Malaysia, October 12 – 14, 2023
- Member of Institutional Animal Ethics Committee, PENTAGRIT Chennai.
- Life Member Indian Science Congress Association.
- Guest Editor in Emerging Trends in Metabolites – STM journals
- Reviewer for Biocatalysis and Agricultural Biotechnology
- Reviewer for Applied Biochemistry and Biotechnology.
- Reviewer for Pharmacology Reports.
- Member for UG, PG board of studies at Anna University.
- Best Poster Award at the International Conference on Naturopathy, Nanotechnology, Nutraceuticals and Immunotherapy in cancer research- ICN3IC21 organized by Association of Cancer Education and Research ACER & B.S. Abdur Rahman Crescent Institute of Science & Technology, June 11-12, 2021
- Women Scientist Award at the International Conference on Environment, Agriculture, Human and Animal Health – ICEAHAH21, June 5-6, 2021
- Best Oral Presentation Award at the International Conference on Environment, Agriculture, Human and Animal Health ICEAHAH21, June 5-6, 2021
- SPER Best Ph.D. student Award at the 7th Annual International Conference and Exhibition SPER 2018, February 23 – 24, 2018
- Won cash award for Best Oral Presentation at National conference on Biomarkers from Research to Clinical Practice BRCP 2017 organized by Dept. of Biochemistry, Meenakshi College for Women, Chennai on 30 & 31st January 2017
- Best Paper Award at the National symposium on Cancer Research: A Global Scenario Organized by Life Intelligentsia Foundation & Frontier Mediville, Gummidipoondi on 19th June 2014.
- Rank IV at PG Level, Madurai Kamaraj University (2000)
Research areas
- Molecular Biology and Biochemistry
- Cancer Therapeutics
- Cell signaling
- Molecular diagnosis of disease
- Phyto Medicine
- Drug discovery and design
Research outcomes
a. Research grants: Completed 02
Crescent seed money- Development of Hypoxia Inducible factor 1 α based angiogenic inhibitor for management of triple negative breast cancer, 2023- 2024, Rs: 83,000.
Tamil Nadu State Council for Science and Technology (TNSCST), Student Project Scheme, Exploring the Anti-oxidant and Anti-inflammatory properties of Gymnemic acid in breast cancer (S1PR1/NLRP3 pathway), 2024-2025, Rs 7,500.
b. Publications: 14
Number of Research Publications (total publications from Crescent and other institutions- no list is required)
- International journals: 14
- National journals: 1
- Conference presentations: 60
- Invited talks delivered: 5
- Patents: filed: 2 Published: 2
List of publications
- Nishmaa S, Ranganathan V, Begum SMNFM*. Berberine chloride inhibits proliferation and angiogenesis in triple-negative breast cancer by down-regulating HIF-1α/VEGF/Ang path-way. Bangladesh J Pharmacol. 20(2), 72-77, 2025 DOI: 10.3329/bjp.v20i2.80837 (Scopus Indexed) (Impact factor 1.4) (Q3)
- Nishmaa S, Ankita Rao, Fazeela Mahaboob Begum S.M* Anticancer and antimetastatic potentials of crude extracts from Dictyota bartayresiana in triple negative breast cancer – an in vitro approach. Bangladesh J Pharmacol. 19(4),114–121,2025. https://doi.org/10.3329/bjp.v19i4.77912. (Scopus Indexed) (Impact factor 1.4) (Q3)
- S. Jazeera Mariyam, S.M. Fazeela Mahaboob Begum*. Cytotoxic marine terpenes from Hypnea valentiae inhibit cell viability and migration of TNBC cells under in vitro conditions. Research Journal of Pharmacy and Technology. 17(8), 3575-1, 2024. DOI: 10.52711/0974-360X.2024.00558 (Scopus Indexed)(Impact factor 0.8) (Q2)
- Megasri S, Fazeela Mahaboob Begum S.M. Phytochemical characterization by GC-MS and in vitro evaluation of antiproliferative and antimigratory studies of Leucas aspera leaf extracts on MDA-MB-231cellline. BioTechnologia, 105(1),55-68, 2024 https://doi.org/10.5114/bta.2024.135642 (Scopus Indexed) (Impact factor 0.9) (Q4)
- S.M. Fazeela Mahaboob Begum, S. Hemalatha. Marine Natural Products – A vital source of novel Biotherapeutics. Current Pharmacology Reports. 8, 339–349,2022. https://doi.org/10.1007/s40495-022-00295-8. (Scopus indexed) (Impact factor 1.524) (Q2)
- Shree TJ, Poompavai S, Begum SMFM, Sree VG, Hemalatha S. Cancer-Fighting Phytochemicals: Another Look. J Nanomedine Biotherapeutic Discov, 9 (1), 162 – 169,2019. DOI:10.4172/2155-983X.1000162
- S.M.Fazeela Mahaboob Begum, S.Hemalatha, Gelidiella acerosa compounds target NFB cascade in lung adenocarcinoma. Applied Biochemistry and Biotechnology, 2022. 194, 1566–1579. https://doi.org/10.1007/s12010-021-03761-z (Scopus indexed) (Impact factor 3.094) (Q2).
- S.M. Fazeela Mahaboob Begum SM, Kalai chitra, Benin Joseph, Raji Sundarrajan, Hemalatha S. Gelidiella acerosa inhibits lung cancer proliferation. BMC Complementary and Alternative Medicine, 18, 104-118, 2018, https://doi.org/10.1186/s12906-018-2165-1, (Scopus Indexed) (Impact factor 3.47) (Q1)
- S. Sathish Kumar, M. Fazeela, S. Saroj Kumar, S. Kulandaisamy, S. Mahasampath Gowri, S. Hemalatha & K. K. Balasubramanian Synthesis, characterization, In vitro, and in silico studies of 4-(2′-hydroxybenzoyl) and 4-(2′-hydroxynaphthoyl)-thiabenzene-1- methyl-1-oxides, Synthetic Communications, 48 (5) 553-560 2018. DOI: 10.1080/00397911.2017.1411950. (Scopus and WOS indexed) (Impact Factor 1.937) (Q3)
- S.M. Mahaboob Begum, S.Hemalatha. Characterization, In silico and In vitro determination of Antidiabetic and Antiinflammatory potential of ethanol extract of Sargassum wightii. AJPCR, 10(4), 2017, https://doi.org/10.22159/ajpcr.2017.v10i4.16742. (Scopus Indexed) (Impact factor 0.5)
- S.M. Fazeela Mahaboob Begum, S.Priyaa, S.Hemalatha. In vitro and In silico analysis of the antioxidant and angiogenic potential of Padina tetrastomatica” International Journal of Chem Tech Research, 10(2); 223 – 230, 2017
- S.M. Fazeela Mahaboob Begum, Zakia Fathima, S.Priyaa, Raji Sundarrajan, S.Hemalatha. Indian Medicinal Plants Target Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) to Control Diabetes – An in silico and in vitro Approach. OMICS, Gen. Med, 5(2), 289 – 296; 2017 doi:10.4172/2327-5146.1000289
- S.M. Fazeela Mahaboob Begum, S.Priyaa, Raji Sundarrajan, S.Hemalatha. Novel anticancerous compounds from Sargassum wightii: in silico and in vitro approaches to test the antiproliferative efficacy. SPER, JAPER, l7(2), 2017. (Scopus Indexed) (Impact factor 1.4) (Q3)
Book Chapters (National/international)
- Kathir, & S.M. Fazeela Mahaboob Begum*. Role of nanoparticles in cancer therapy Technological Innovations In Health, Agriculture and Environment. ISBN: 978-93-341-3131-4 Pg. No 203-219.
- Sameera Siddique, Mohamed Shafil S., & Fazeela Mahaboob Begum S.M*. Bioremediation: An eco-friendly solution for combating environmental pollution. Technological Innovations In Health, Agriculture and Environment. ISBN: 978-93-341-3131-4 Pg. No 173-187
- J, Sri Vidhya Yamini.V, Megavardhini. P, Fazeela Mahaboob Begum SM*. The role of bioprospecting in pharmaceutical and nutraceutical industries: A short review. Current Research in Bioprospecting and its Application. Vol I ISBN: 978-81-980173-9-0 Pg. No 192-202.
- Harshitha, Ashwini V, Anushri R, Varshini G and Fazeela Mahaboob Begum S.M*. Marine Bioprospecting – Exploration of Marine Natural Products In Drug Discovery. Current Research in Bioprospecting and its Application. Vol I ISBN: 978-81-980173-9-0 Pg. No 240-254
- Dharshini G, Harini I, Ranganayaki R and Fazeela Mahaboob Begum SM and Venkatalakshmi Ranganathan. Innovations In Food And Nutrition: Exploring New Sources, Supplements, And Functional Foods. Current Research in Bioprospecting and its Application. Vol I ISBN: 978-81-980173-9-0 Pg. No 317-329
- S Mohamed Shafil, Sameera Siddique, N. Nazar, and Fazeela Mahaboob Begum SM*. Plant Bio-prospecting for Antimicrobial Resistance: The Search for new Antibiotics in Current Research in Bioprospecting and its Application. Vol II ISBN: 978-81-980173-9-0 Pg. No 1-15
- A, Hajira Parveen Mohideen Subytha Asrin, Fazeela Mahaboob Begum SM*. A Short Review on The Advances In Innovations and Applications In Biotechnology. Current Research in Bioprospecting and its Application. Vol II ISBN: 978-81-980173-9-0 Pg. No 56-66
- Shalini M, Janani U, Sandhiya T and Fazeela Mahaboob Begum SM, Venkatalakshmi Ranganathan. Exploring The Applications of Microorganisms In Healthcare, Bioremediation and Cosmetic Industries. Current Research in Bioprospecting and its Application. Vol II ISBN: 978-81-980173-9-0 Pg. No 219-233
- S.M. Fazeela Mahaboob Begum, V. Gowri Sree, Ignacio Camarillo,Shree TJ, Poompavai S, Hemalatha. Everyday Phytochemicals for Cancer: Another Look. 2020/BP/1741F (Book Chapter).
Book Authored
- S.M. Fazeela Mahaboob Begum, Venkatalakshmi Ranganathan, Harshitha, Anushri, Ashwini. A Practical Hand Book for Biotechnology, Microbiology & Biochemistry. First Edition 2024. BP International. Print ISBN: 978-81-982889-4-3, eBook ISBN: 978-81-982889-3-6 ISBN 978-81-982889-4-3(Print)DOI: https://doi.org/10.9734/bpi/mono/978-81-982889-4-3
Research guidance
Ph.D: Ongoing: 03
List of Scholars ongoing:
| S.No | Name of the scholar | Title of the Ph.D | Year of registration |
1 | Mrs. V. JULA | Evaluating the anticancer, anti-metastatic, and anti-angiogenic efficiencies of marine brown algal compounds in managing triple native breast cancer (TNBC) under in vitro and in vivo conditions | 2024 |
2 | Ms. S. Priyangha | Exploring the anticancer and immunomodulatory properties of plant metabolites on tumor microenvironment in cancer | 2025 |
3 | Ms Ganishka | Exploring the pharmaceutical properties of bioactive compounds from marine algae | 2025 |
M.Sc:
Completed projects: 08; Ongoing Projects: 19
List of M. Sc., Projects completed
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
| 1. | H. Kursith Irfan | Isolation, Characterization of Flavonoids from Celosia Argenta and Evaluation of Antioxidant and Anticancer Activities Under In Vitro Conditions | 2025 | Publication:1 Communicated Conference presentation:2 |
| 2. | Mohamed Sameer | Isolation, Characterization of Phytocompounds from Marine Red Algae Portieria Hornemannii and Evaluation of Antioxidant, Antiinflammatory and Anticancer Activities | 2025 | Conference presentation:1 |
| 3. | Afnan Baisal | Isolation Characterization of Terpenoids from Curcuma Caesia Rhizome and Evaluation Of Antioxidant, Anticancer Activities | 2025 | |
| 4. | Ummu Hajara | Formulation and evaluation of carrageenan-based fish feed to enhance growth in freshwater ornamental fish. | 2024 | Conference presentation:2 |
| 5. | Pavithra S | Screening the antioxidant, anti-inflammatory and antibacterial efficacies of Mukia maderaspatana and development of functional food to combat upper respiratory tract infections | 2024 | Conference presentation:2 |
| 6. | Ashutosh Kushwaha | Anti-metastatic evaluation and characterization of compound berberine chloride and its significant effect on HIF 1- α pathway and its associated proteins under in-vitro and in-silico conditions. | 2024 | Publication:1 Communicated Conference presentation:2 |
| 7. | Rooba Shree | Evaluating the anti-angiogenic activity of berberine chloride in triple negative breast cancer | 2024 | Conference presentation:2 |
| 8. | Jazeera Mariyam S | Isolation, characterization and evaluation of the antiproliferative and antiinvasive efficacies of terpenes from marine red algae Hypnea valentiae under in vitro and in silico conditions | 2023 | Publication:1 Conference presentation:2 |
B.Tech : Completed Projects:04
List of B.Tech., Projects completed
| S.No | Name of the student | Title of the project | Year of award | Outcomes |
| 1 | Ashwini V | Isolation, characterization of gymnemic acid, and evaluating its antioxidant properties under In silico and in vitro conditions | 2025 | Publication:1 communicated Conference presentation:5 |
| 2 | Anushri. R | Exploring the Antioxidant, Anti-Inflammatory and anticancer activities of isolated Punarnavine from Boerhavia diffusa plant | 2025 | Publication:1 communicated Conference presentation:4 |
| 3 | Harshitha B | Evaluating the Anti-Inflammatory Properties of Lagenaria siceraria under In Vitro Conditions | 2025 | Publication:1 communicated Conference presentation:5 |
| 4 | Varshini G | Formulation of Glucosinolate based moisturizer from Brassica Var Italica | 2025 | Publication:1 communicated Conference presentation:3 |
Mentorship for student startup companies: 01
| Name of student | Program | Name of the company | Description | Grants received |
| Ummu Hajara | M.Sc Microbiology | Jazza Solutions | Utilization of marine natural products in aquaculture | – |
Student Startup companies incorporated: 01
| S.No | Name of the product | Name of the product |
| 1 | Fish O Car | Fish feed from marine algae |
