Dr. K.Karthikeyan

Edcuation

Educational Background

Teaching and Research Experience

Sponsored Project

• December 2019 – December 2021: Triazole based new functional chromophores for optoelectronic and biological applications, Tamil Nadu State Council of Science and Technology, Chennai, Project Cost: Rs. 3,20,000/- On going
• March 2014- April 2017: Applications of gold catalysis for the synthesis of bioactive heterocycles and natural product mimic, Fast Track for Young Scientist, DST-SERB, Govt. of India, Project Cost: Rs. 19,66,000/- Completed.

Research Guidance

• Number of PhD guidance: 2 (Completed), 2 (Pre-Synopsis), 1 (Ongoing).
  Dr. D. Gangaprasad, PhD awarded September 2018.
  Dr. M. Vadivelu, PhD awarded December 2020.
  Number of M.Sc. project guidance: 7 (Completed), 4 (Ongoing).

List of Publication

Peer reviewed articles: 33; h-Index: 13; i10 index: 16; Cumulative impact factor: 89.24; Average impact factor/publication: 2.97

At B S Abdur Rahman Crescent Institute of Science and Technology (As Guide)

• Tayyala Kiranmye, Murugan Vadivelu, Deviga Magadevan, Sugirdha Sampath, Kannabiran Parthasarathy, Noor Aman* and Kesavan Karthikeyan*, Sunlight Assisted Photocatalytic Sustainable Synthesis of 1,4-Disubstituted 1,2,3-Triazoles and Benzimidazoles Using TiO₂-Cu₂(OH)PO₄ Under Solvent-free Condition, ChemistrySelect 2021 (In press). Impact Factor : 1.811. ISSN : 2365-6549.
• Tayyala Kiranmye, Murugan Vadivelu, Sugirdha Sampath, Kesavan Muthu, Kesavan Karthikeyan, Ultrasound-assisted catalyst free synthesis of 1,4-/ 1,5-disubstituted-1,2,3-triazoles in aqueous medium, Sustainable Chemistry and Pharmacy 19 (2021) 100358. Impact Factor : 3.294. ISSN : 2352-5541.
• Sugirdha Sampath, Murugan Vadivelu, Radhika Ravindran, Paramasivan T. Perumal, Veerapandian Velkannan and Kesavan Karthikeyan, Synthesis of 1,2,3-Triazole Tethered 3-Hydroxy-2-oxindoles: Promising Corrosion Inhibitors for Steel in Acidic Medium and Their Anti-Microbial Evaluation, ChemistrySelect 2020, 5, 2130 – 2134. Impact Factor : 1.811. ISSN : 2365-6549.
• Murugan Vadivelu, Sugirdha Sampath, Kesavan Muthu, Kesavan Karthikeyan, Chandrasekar Praveen, “Harnessing the TEMPO catalyzed aerobic oxidation for Machetti−DeSarlo reaction towards sustainable synthesis of isoxazole libraries” J. Org. Chem. 2019, 84, 13636-13645. Impact Factor : 4.335. ISSN : 0022-3263.
• D. Gangaprasad, J. Paul Raj, K. Karthikeyan, R. Rengasamy, M. Kesavan, M. Vajjiravel, J. Elangovan, “A new route to 1,2,3-triazole fused benzooxazepine and benzodiazepine analogues through metal-free intramolecular azide-olefin oxidative cycloaddition” Tetrahedron Lett. 2019, 60, 151164. Impact Factor : 2.227. ISSN : 0040-4039.
• D. Gangaprasad, J. Paul Raj, K. Karthikeyan, R. Rengasamy, J. Elangovan, “An Efficient One‐Pot Synthesis of 1,2,3‐Triazole‐Fused Chromenes/Quinolinesvia Oxidative [3+2] Cycloaddition followed by Reductive Cyclization” Adv. Synth. Cat. 2018, 360, 4485-4490. Impact Factor : 5.851. ISSN : 1615-4169.
• J. Paul Raj, D.Gangaprasad, K.Karthikeyan, R.Rengasamy, M.Kesavan, M.Venkateswarulu, M.Vajjiravel and J.Elangovan, “A new route to synthesis of substituted pyrazoles through oxidative [3+2] cycloaddition of electron deficient alkenes and diazocarbonyl compounds”Tetrahedron Lett.2018, 59, 4462-4465. Impact Factor : 2.227. ISSN : 0040-4039.
• John Paul Raj, Dasari Gangaprasad, Murugesan Vajjiravel ,Kesavan Karthikeyan, Jebamalai Elangovan, “CuO-Nanoparticles catalyzed synthesis of 1,4-disubstituted-1,2,3-triazoles from bromoalkenes” Journal of Chemical Sciences, 2018, 130: 44. Impact Factor : 1.406. ISSN : 0973-7013.
• M. Vadivelu, A. A. Raheem, S. Sugirdha, G. Bhaskar, K. Karthikeyan, and C. Praveen, “Gold catalyzed synthesis of tetrahydropyrimidines and octahydroquinazolinesunder ball milling conditions and evaluation of anticonvulsant potency” Arkivoc 2018, iii, 90- 101. Impact Factor : 1.253. ISSN : 1551-7012.
• M. Vadivelu, S.Sugirdha, P.Dheen Kumar, Y. Arun, K. Karthikeyan and C. Praveen, “Solvent-free implementation of two dissimilar reactions using recyclable CuO nanoparticles under ball-milling conditions: Synthesis of new oxindole-triazolepharmacophores” Green Chemistry, 2017, 19, 3601-3610. Impact Factor : 9.480. ISSN :1463-9270.
• M. P. Kesavan, S. Ayyanaar, K. Karthikeyan, G. Rajagopal, P. Athappan, J. Rajesh,“DNA interaction and cleavage studies of ancillary chiral ligand and N,N-donor ligands coordinated platinum(II) complexes”Applied Organometallic Chemistry, 2017, 31, e3868. Impact Factor : 3.14. ISSN : 1099-0739.
• D. Gangaprasad, J. Paul Raj, T. Kiranmye, K. Karthikeyan, J. Elangovan,“A New Example of Organo Click Reactions: TEMPO-Promoted Oxidative Azide-Olefin Cycloaddition for the Synthesis of 1,2,3-Triazoles in Water“ Eur. J. Org. Chem.2016, 5642-5646. Impact Factor : 2.899. ISSN :1099-0690.
• D. Gangaprasad, J. Paul Raj, T. Kiranmye, R. Sasikala, K. Karthikeyan, S. Kutti Rani, J. Elangovan, “A tunable route to oxidative and eliminative [3+2] cycloadditions of organic azides with nitroolefins: CuO nanoparticles catalyzed synthesis of 1,2,3-triazoles under solvent-free condition”Tetrahedron Lett. 2016, 57, 3105-3108. Impact Factor : 2.227. ISSN : 0040-4039.
• R. Sasikala, K. Karthikeyan, D. Easwaramoorthy, I. Mohammed Bilal, S. Kutti Rani,“ Photocatalytic degradation of trypan blue and methyl orange azo dyes by cerium loaded CuO nanoparticles”, Environmental Nanotechnology, Monitoring & Management, 2016, 6, 45-53. Cite Score : 5.4. ISSN : 2215-1532.
• R. Sasikala, S. Kutti Rani, K. Karthikeyan, D. Easwaramoorthy and I. Mohammed Bilal,“Detoxification of Methyl Orange and Trypan Blue Dyes by using Erbium loaded CuO nanoparticles”International Journal of Chem Tech Research, 2016, 9, 440-452.ISSN : 2455-9555.
• R. Sasikala, S. Kutti Rani, D. Easwaramoorthy and K.Karthikeyan, “Lanthanum loaded CuO nanoparticles: synthesis and characterization of a recyclable catalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles and propargylamines”RSC Adv., 2015, 5, 56507–56517. Impact Factor : 3.119. ISSN : 2046-2069.
• R. Sasikala, D. Easwaramoorthy, K. Karthikeyan, I.Mohammed Bilal and S. Kutti Rani,“Oxidative degradation of glycyl–glycine by PMS in the neutral medium”Journal of Chemical and Pharmaceutical Sciences,2015, Special Issue 8, 13-20. ISSN : 0975-7384.
• K. Karthikeyan, R. Senthil Kumar, P. Dheenkumar and Paramasivan T. Perumal,“Solvent and catalyst free route to 3-indolyl glycoconjugates: synthesis of sugar tethered isoxazolines and isoxazoles from 3-indolyl nitroalkanes”RSC Adv., 2014, 4, 27988-27997. Impact Factor : 3.119. ISSN : 2046-2069.

At CSIR-Central Leather Research Institute (As PhD Student)

• S. Kandhasamy, K. Karthikeyan, K. Ramachandiran, D. Muralidharan, P. T. Perumal,“Aza-Morita-Baylis-Hillman reaction of maleimides with azodicarboxylates under neat conditions”J. Chem. Sci. 2013, 125, 967-974. Impact Factor : 1.406. ISSN : 0973-7013.
• M. Damodiran, K. Karthikeyan, D. Muralidharan and Paramasivan T. Perumal, “Novel Sulfamic Acid–Promoted Synthesis of 3-Alkylidene Indolone Derivatives in the Presence of Aniline via One-Pot Multicomponent Reaction”Synthetic Communications, 2013, 43, 645–655. Impact Factor : 1.796. ISSN : 1532-2432.
• K. Ramachandiran, K. Karthikeyan, T. Nandhakumar, D. Muralidharan, P.T. Perumal,“Stereoselective Synthesis of IsoxazolinobenzoxepanesviaIntramolecular Nitrile Oxide Cycloaddition”Synthesis, 2011, 3277-3286. Impact Factor : 2.675. ISSN : 0039-7881.
• T. S. Ramyaa Lakshmi, N. Shanmugasundaram, S. Shanmuganathan, K. Karthikeyan,J. Meenakshi and Mary Babu, “Controlled release of 2, 3 desulfated heparin exerts its anti-inflammatory activity by effectively inhibiting E-selectin”Journal of Biomedical Materials Research Part A, 2010, 95A, 118–128. Impact Factor : 3.525. ISSN : 1552-4965.
• K. Karthikeyan, N. Saranya, A. Kalaivani, P. T. Perumal,“Synthesis of Spiropyrrolidines and Spiropyrrolizidines by AzomethineYlideCycloaddition of Baylis–Hillman Adducts Derived from N-Methyl Maleimide”Synlett. 2010, 2751-2754. Impact Factor : 2.006. ISSN : 0936-5214.
• K.Karthikeyan, P.M.Sivakumar, M.Doble, P.T.Perumal,“Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines”European Journal of Medicinal Chemistry, 2010, 45, 3446-3452. Impact Factor : 5.572. ISSN : 0223-5234.
• K. Ramachandiran, K. Karthikeyan, D. Muralidharan, P.T. Perumal,“Synthesis of isoxazolobenzoxepanesvia Michael addition of indoles to nitroalkenes and sequential intramolecular nitrile oxide cycloaddition” Tetrahedron Lett.2010, 51, 3006-3009. Impact Factor : 2.227. ISSN : 0040-4039.
• R. Senthil Kumar, K. Karthikeyan, B.V.N. Phanikumar, D. Muralidharan and P. T. Perumal,“Synthesis of densely functionalised C-glycosides by a tandem Wittig olefination-oxy Michael addition pathway”Carbohydrate Research, 2010, 345, 457-461. Impact Factor :1.841. ISSN :0008-6215.
• K.Karthikeyan, R.Senthil Kumar, D.Muralidharan and P.T.Perumal,“Diastereoselective synthesis of pyrrolidines via 1,3-dipolar cycloaddition of a chiral azomethineylide”Tetrahedron Lett.2009, 50, 7175-7179. Impact Factor : 2.227. ISSN : 0040-4039.
• C. Praveen, K. Karthikeyan, P.T. Perumal, “Efficient synthesis of 3-substituted indoles through a domino gold(I) chloride catalyzed cycloisomerization/C3-functionalization of 2-(alkynyl)anilines”Tetrahedron2009, 65, 9244-9255. Impact Factor : 2.223. ISSN : 0040-4020.
• K.Karthikeyan and P.T.Perumal,“Synthesis of Highly Functionalized Spirobenzofuranols and Spirobenzofuranones by Baylis-Hillman Reaction”Synlett. 2009, 2366-2370. Impact Factor : 2.006. ISSN : 0936-5214.
• K. Karthikeyan, T. Veenus Seelan, K. G. Lalitha, P. T. Perumal,“Synthesis and antinociceptive activity of pyrazolylisoxazolines and pyrazolylIsoxazoles”Bioorg. Med. Chem. Lett. 2009, 19, 3370–3373. Impact Factor : 2.572. ISSN :0960-894X.
• R.Senthil Kumar, K. Karthikeyan and Paramasivan T. Perumal,“An efficient procedure for the TEMPO-catalyzed oxidation of alcohols to aldehydes and ketones using ferric chloride hexahydrate as terminal oxidant”Can. J. Chem. 2008, 86, 720-725. Impact Factor : 1.117. ISSN :1480-3291.
• Kesavan Karthikeyan, Paramasivan T. Perumal, SundaresanEtti and GuruswamyShanmugam,“Diastereoselective syntheses of pyrazolylisoxazolidines via 1,3-dipolar cycloaddition”Tetrahedron2007, 63, 10581-10586. Impact Factor : 2.223. ISSN : 0040-4020.
• V. Sridharan, K. Karthikeyan and S. Muthusubramanian,“Unexpected multicomponent reaction of 2/4-methoxyarylaldehydes with arylhydroxylamines and maleic anhydride: a novel synthesis of unsymmetrical diarylamines” Tetrahedron Letters, 2006, 47, 4221–4223. Impact Factor : 2.227. ISSN : 0040-4039.

Invited Talk

• Spectral Interpretation of Organic and Biomolecules using NMR and Mass – Karpagam College of Pharmacy, Coimbatore in association with Indian Pharamaceutical Association, Coimbatore on 23th October 2020
• Introduction to NMR and Mass and Interpretation of Bioactive Molecules – G. P Pharmacy College, Jolarpet, Tirupattur on 14th December 2019
• Analytical techniques – Chromatography – Dr. M.G.R. Educational And Research Institute, Chennai on 6th April 2017

Membership in professional societies:

• Chemical Research Society of India (CRSI) – Life Time Member

Awards

• DST Young Scientist Award-2014
• Postdoctoral Fellowship; “Research in Paris 2010” awarded by Maire de Paris.
• Senior Research Fellowship 2008; awarded by Council of Scientific and Industrial Research (CSIR-SRF).
• Junior Research Fellowship 2006; awarded by Council of Scientific and Industrial Research (CSIR-JRF) and National Eligibility Test (NET).
• Qualified Graduate Aptitude Test in Engineering (GATE-2006, GATE-2005) IIT, India.
• Prof.C.Srinivasan Endowment Medal and Dr.T.P.Meenashisundaran Endowment Prize for first rank in MSc Chemistry.
• Maveeran Sundarlingam Endowment Scholarship.